Application of Asymmetric Flow Field-Flow Fractionation coupled to Multi-Angle Light Scattering (A4F-MALS) for the Characterization of AAV Products

Time: 4:20 pm
day: Day One

Details:

  • Development of an A4F-MALS method to evaluate important quality attributes of AAV products, including purity, percent aggregation, capsid particle concentration, and putative empty/full ratio will be discussed
  • Key examples of its application on AAV samples to assess batch-tobatch consistency, effects of accelerated stress, and stoichiometry of AAV-mAb complexes will be presented

Speakers: